Coagulation and fibrinolysis in hepatic cirrhosis

Significance of intravascular coagulation and fibrinolysis in acute hepatic failure.

Twenty-two patients with acute hepatic failure were studied to determine the incidence and magnitude of intravascular coagulation and fibrinolysis and their relation to the severity of bleeding and prognosis. The mean platelet count, Thrombotest, plasminogen activator, and plasminogen were reduced; the reduction in fibrinogen was not statistically significant. Fibrin/fibrinogen degradation prod...

Coagulation and fibrinolysis after injury.

Blood coagulation, fibrinolysis and exercise.

Coagulation and Fibrinolysis in Injured Patients.

Serial changes in coagulation and fibrinolysis studied among 42 patients admitted to hospital with a wide variety of injuries are reported. The first hours after trauma are dominated by an acceleration of fibrinolysis (clot lysis) and clotting time which are often followed by an abrupt rebound to prolonged fibrinolysis and normal clotting. Evidence is presented that acceleration of fibrinolysis...

Abnormal Plasminogen-plasmin System Activity (fibrinolysis) in Patients with Hepatic Cirrhosis: Its Cause and Consequences.